Phone
(608) 262-7341Website
View WebsiteOffice Location
4147 UW Med Fndtn Centennial Bldg
1685 Highland Ave
Madison, WI 53705
Dr. Lamming is an Associate Professor in the Department of Medicine Division of Endocrinology, Diabetes and Metabolism at the UW-Madison School of Medicine and Public Health, and is a Research Health Scientist at William S. Middleton Memorial Veterans Hospital. Postdoctoral, Ph.D. students, M.D. students and undergraduates interested in pursuing research in the Lamming lab should contact Dr. Lamming directly at dlamming@medicine.wisc.edu.
Dr. Lamming is a member of the following centers and graduate training programs:
- Cell & Molecular Biology (CMB) Graduate Program
- Cellular and Molecular Pathology (CMP) Graduate Program
- Comparative Biomedical Sciences (CBMS) Graduate Program
- Endocrinology and Reproductive Physiology (ERP) Graduate Program
- Genetics Training Program
- Interdepartmental Graduate Program in Nutritional Sciences (IGPNS)
- Molecular & Cellular Pharmacology (MCP) Program
- Molecular & Environmental Toxicology Graduate Program
- UW Carbone Comprehensive Cancer Center
- UW-Madison Institute on Aging
Education
- BS, Massachusetts Institute of Technology
- PhD, Harvard University
- Postdoc, Whitehead Institute for Biomedical Research
- Joined the UW-Madison Faculty in 2014.
- Growth Differentiation Factor 15 Elevation in the Central Nervous System Is Associated With Failure to Thrive in Alexander Disease
- Lifelong restriction of dietary valine has sex-specific benefits for health and lifespan in mice
- Dietary isoleucine content modulates the metabolic and molecular response to a Western diet in mice
- Restriction of individual branched-chain amino acids has distinct effects on the development and progression of Alzheimer's disease in 3xTg mice
- Fasting is required for many of the benefits of calorie restriction in the 3xTg mouse model of Alzheimer's disease
- Tissue-Specific Effects of Dietary Protein on Cellular Senescence Are Mediated by Branched-Chain Amino Acids
- Rapamycin Does Not Compromise Exercise-Induced Muscular Adaptations in Female Mice
- Ketogenesis is dispensable for the metabolic adaptations to caloric restriction
- Dietary lipids are largely deposited in skin and rapidly affect insulating properties
- Rapamycin does not compromise physical performance or muscle hypertrophy after PoWeR while intermittent rapamycin alleviates glucose disruptions by frequent rapamycin
Our goal is to understand how nutrient-responsive signaling pathways can be harnessed to promote health and longevity. Rapamycin, an inhibitor of the protein kinase mTOR, can improve both health and longevity in model organisms including mammals. Understanding and manipulating the mTOR signaling pathway through dietary, pharmaceutical or genetic interventions may provide insight into the treatment of age-related diseases, including diabetes, Alzheimer’s disease, cancer, and Hutchinson-Gilford Progeria Syndrome.