Daniel Amador-Noguez

Professor of Bacteriology

Impact of microbial bile acid transformations on host physiology

Email

amadornoguez@wisc.edu

Website

Photo of Daniel Amador-Noguez

Publications

Discovery of metabolites produced by reactions between central carbon metabolites and cysteine that mark inflammatory macrophages
Nicholas L Arp, Felicia Deng, Jorgo Lika, Gretchen L Seim, Paulo Falco Cobra, Carlos Mellado Fritz, Steven V John, Swetha Rathinaraj, Bridget E Shields, Daniel Amador-Noguez, Katherine Henzler-Wildman, Jing Fan
March 27, 2026
Metabolic imbalance limits fermentation in microbes engineered for high-titer ethanol production
Bishal Dev Sharma, Eashant Thusoo, David M Stevenson, Daniel Amador-Noguez, Lee R Lynd, Daniel G Olson
March 25, 2026
Genetic and metabolic drivers of membrane remodeling in <em>Clostridium thermocellum</em> under alcohol stress
Eashant Thusoo, Tyler Jacobson, Bishal D Sharma, Isabella M Colón, Lee R Lynd, Daniel G Olson, Daniel Amador-Noguez
March 5, 2026
Investigation of bile salt hydrolase activity in human gut bacteria reveals production of conjugated secondary bile acids
Lauren N Lucas, Mallikarjun Jillella, Lea E Cattaneo, Bhavana Gangwar, Qijun Zhang, A P Clay, Robert L Kerby, David M Stevenson, Helen E Blackwell, Federico E Rey, Daniel Amador-Noguez
February 23, 2026
GPR41 deficiency alters the gut microbiota-bile acid axis, reduces ileal expression of <em>Npc1l1</em>, and attenuates hypercholesterolemia in male mice
Evan R Hutchison, Jillella Mallikarjun, Jung Ha Byun, Lauren N Lucas, Kazuyuki Kasahara, Michael Tallon, Qijun Zhang, Daniel Amador-Noguez, Yongjun Liu, Vanessa A Leone, Brian W Parks, Federico E Rey
December 15, 2025
Physiological and metabolic responses of <em>Zymomonas mobilis</em> to lignocellulosic hydrolysate
Julio Rivera Vazquez, Edna Trujillo, Zach Wenger, Michael Botts, Joshua J Coon, Daniel Amador-Noguez
September 17, 2025
Thermodynamics shapes the <em>in vivo</em> enzyme burden of glycolytic pathways
Daven B Khana, Annie Jen, Evgenia Shishkova, Kirsten Fisher, Eashant Thusoo, Jonathan Williams, Alex Henkel, David M Stevenson, Joshua J Coon, Daniel Amador-Noguez
September 16, 2025
Reconstruction of a resource balance analysis model of Clostridium thermocellum examines the metabolic cost of glycolytic and cellulosome enzymes
Thomas C Willis, Wheaton L Schroeder, Daven B Khana, Xuejun Qian, Sanjeev Dahal, Daniel Amador-Noguez, Costas D Maranas
September 10, 2025
Gut microbes mediate the synergistic effects of dietary cholesterol and saturated fat in driving fibrosing MASH
Jake B Hermanson, Samar A Tolba, Md Amran Gazi, Evan A Chrisler, Manpreet Kaur, Ashley M Sidebottom, Yongjun Liu, Guillermo Martinez-Boggio, Lauren N Lucas, Daniel Amador-Noguez, Federico E Rey, Vanessa A Leone
August 8, 2025
Portal bile acid composition and microbiota along the <em>murine</em> intestinal tract exhibit sex differences in physiology
François Reichardt, Lauren N Lucas, Lydia Okyere, Jim Choi, Daniel Amador-Noguez, Christopher A Gaulke, Sayeepriyadarshini Anakk
August 5, 2025