Dudley Lamming

    Associate Professor of Endocrinology

    School of Medicine and Public Health

    The regulation of healthy aging by what, when, and how much we eat.

    Phone

    (608) 262-7341

    Office Location

    4147 UW Med Fndtn Centennial Bldg
    1685 Highland Ave
    Madison, WI 53705

    Photo of Dudley Lamming

    Dr. Lamming is an Associate Professor in the Department of Medicine Division of Endocrinology, Diabetes and Metabolism at the UW-Madison School of Medicine and Public Health, and is a Research Health Scientist at William S. Middleton Memorial Veterans Hospital. Postdoctoral, Ph.D. students, M.D. students and undergraduates interested in pursuing research in the Lamming lab should contact Dr. Lamming directly at dlamming@medicine.wisc.edu.

    Dr. Lamming is a member of the following centers and graduate training programs:

    Education

    • BS, Massachusetts Institute of Technology
    • PhD, Harvard University
    • Postdoc, Whitehead Institute for Biomedical Research
    • Joined the UW-Madison Faculty in 2014.
    • Female resistance to the metabolic benefits of protein restriction is reversed by ovariectomy in mice
      Bailey A Knopf, Isaac Grunow, Brady Anderson, Tareq Rihawi, Michelle M Sonsalla, Mariah F Calubag, Reji Babygirija, Yang Liu, Fan Xiao, Chung-Yang Yeh, Dudley W Lamming
    • Toward actionable interventions in human aging (12th ARDD meeting, 2025)
      Aleksandr Dekan, Sierra Lore, Ye Eun Yoon, Aisyah Sjöholm, Alexander Tyshkovskiy, Alexey Terskikh, Ana Maria Cuervo, Anastasia Georgievskaya, Andrea Heinz, Andrei Seluanov, Andrew Adams, Andy P Tsai, Anna Murray, Anne Brunet, Anne Marije van Harten, Avi Spier, Ben Shenhar, Bente Klarlund Pedersen, Berthil Clasen, Björn Schumacher, Brian K Kennedy, Charlotte Suetta, Christiane Volbracht, Christoph Kuppe, Clive Cookson, Collin Y Ewald, Cristiana Banila, Daisy Cai, Dario Riccardo Valenzano, Dudley W Lamming, Edward Rudnic, Elias Bou Samra, Emma Teeling, Eric Verdin, Evandro Fei Fang, Fabrizio d'Adda di Fagagna, Fedor Galkin, Garri Zmudze, Heinrich Jasper, In Hwa Jang, Jing-Dong Jackie Han, Jamie Justice, Jan H J Hoeijmakers, Javier María Peralta Ramos, Jean-Marc Lemaitre, Jeroen Aerssens, Joe Betts-LaCroix, John C Newman, Juan Carlos Izpisua Belmonte, Kazuto Kawamura, Kennedy Matsagas Schaal, Kitsu Egerton, Kotb Abdelmohsen, Kristen Fortney, Lars Hartenstein, Laura Niedernhofer, Lida Katsimpardi, Lisa Melton, Lotte Bjerre Knudsen, Luigi Ferrucci, Lykke Sylow, Marco Demaria, Marissa J Schafer, Marta Guasch-Ferré, Martin Borch-Jensen, Maxim Kholin, Michael Antonov, Michael Levitt, Michela Deleidi, Miriam Merad, Morten Meldal, Mourad Topors, Murali Venkatesan, Nathan K LeBrasseur, Niklas Anzinger, Peter Fedichev, Paul Kohlhaas, Peter J Mullen, Priya Singhal, Rafael de Cabo, Riekelt H Houtkooper, Rusty Montgomery, Ryan Smith, Sharon Rosenzweig-Lipson, Sergey Jakimov, Steve Horvath, Steven Austad, Thomas A Rando, Todd White, Tom Zuber, Tomaz Rozmaric, Tony Wyss-Coray, Tuomas Tammela, Vadim N Gladyshev, Vanessa V C Sinatti, Weilan Wang, William Harborne, Xiaodong Liu, Xing Li Wang, Yousin Suh, Yuta Lee, Zane Koch, Alex Zhavoronkov, Morten Scheibye-Knudsen, Daniela Bakula
    • Restriction of Individual Branched-Chain Amino Acids has Distinct Effects on the Development and Progression of Alzheimer's Disease in 3xTg Mice
      Reji Babygirija, Cara L Green, Michelle M Sonsalla, Izabelle Marie F Le, Fan Xiao, Sarah Yandell, Mariah F Calubag, Michaela E Trautman, Anna Tobon, Ryan Matoska, Chung-Yang Yeh, Charles I Opara, Isaac Grunow, Diana Vertein, Sophia Schlorf, Bailey A Knopf, Michael J Rigby, David A Harris, Mark P Keller, Alan D Attie, Luigi Puglielli, Cholsoon Jang, Dudley W Lamming
    • Past, present and future perspectives on the science of aging
      Fabrisia Ambrosio, Maxim N Artyomov, Steven N Austad, Nir Barzilai, Juan Carlos Izpisua Belmonte, Daniel W Belsky, Bérénice A Benayoun, Anne Brunet, Handan Melike Dönertaş, Dena B Dubal, Evandro F Fang, Jerome N Feige, Linda P Fried, David Furman, Xu Gao, Vadim N Gladyshev, Vera Gorbunova, Myriam Gorospe, Jing-Dong J Han, Oskar Hansson, Eiji Hara, Steve Horvath, Nancy Y Ip, George A Kuchel, Matt Kaeberlein, Dudley W Lamming, Becca R Levy, Guang-Hui Liu, Jinkook Lee, Terrie E Moffitt, Tohru Minamino, Linda Partridge, Parminder Raina, Thomas A Rando, John W Rowe, Michal Schwartz, Andrew J Scott, Felipe Sierra, David A Sinclair, Charlotte E Teunissen, Bruno Vellas, Eric Verdin, Keenan A Walker, Ashley E Webb, Tony Wyss-Coray, Ming Xu, Jin-Tai Yu, Alex Zhavoronkov, Yahyah Aman, Anna Kriebs, Qingzhong Ren, Hannah Walters, Sebastien Thuault
    • The Sixth Annual Symposium of the Midwest Aging Consortium
      Ines Sturmlechner, Sarah A Ashiqueali, Hélène Martini, Karla Valdivieso, Ana Catarina Franco, Prashanth Guthikonda, Andrew J Dosch, Luis I Prieto, Niels C Asmussen, Amanda S Latham, James T Redden, Ethan A Leitschuh, Douglas G Mashek, João F Passos, Jhonny Rodriguez-Lopez, T Blake Monroe, David A Bernlohr, Paul D Robbins, Bailey A Knopf, Dudley W Lamming, Matthew J Johnston, Holly M Brown-Borg, Spencer A Tye, Timothy W Rhoads, David M Gate, Bennett G Childs, Darren J Baker, Xinna Li, In Hwa Jang, Christina D Camell, Zachary Miller, Hemali Phatnani, Adam R Konopka, Andrew J Haak, Natalia Vanegas-Avendano, Ramya N Akula, Ajinkya R Limkar, William A Ricke, Scott F Leiser, Jacinta Correia, Hua Bai, Szczepan Olszewski, Kenneth L Seldeen, G R Scott Budinger, Luisa C Morales-Nebreda, Deborah R Winter, Shelly K McCrady-Spitzer, Rozalyn M Anderson, Maria M Mihaylova, Mauricio Rojas, Ana L Mora, Nathan K LeBrasseur, Marissa J Schafer
    • Depletion of individual dietary amino acids induce distinct metabolic and chromatin states
      Spencer A Haws, Yang Liu, Cara L Green, Krittisak Chaiyakul, Pragyan Mishra, Reji Babygirija, Eric A Armstrong, Anusha T Mehendale, Irene M Ong, Dudley W Lamming, John M Denu
    • Ketogenesis is Dispensable for the Metabolic Adaptations to Caloric Restriction
      Chung-Yang Yeh, Alexis L Borgelt, Brynn J Vogt, Alyssa A Clark, Ted T Wong, Isaac Grunow, Michelle M Sonsalla, Reji Babygirija, Yang Liu, Michaela E Trautman, Mariah F Calubag, Bailey A Knopf, Fan Xiao, Dudley W Lamming
    • A low-protein diet drives short- and long-term improvements in metabolic health in a mouse model of sleeve gastrectomy
      Julia Illiano, Cara L Green, Alina Chao, Grace Zhu, Luiz Lopez, Odin Schaepkens, Cholsoon Jang, Dudley W Lamming, David A Harris
    • Growth Differentiation Factor 15 Elevation in the Central Nervous System Is Associated With Failure to Thrive in Alexander Disease
      Tracy L Hagemann, Michelle M Sonsalla, Cora Luzinski, Fernando Zacahua, David A Harris, Dudley W Lamming, Albee Messing
    • Lifelong restriction of dietary valine has sex-specific benefits for health and lifespan in mice
      Mariah F Calubag, Ismail Ademi, Cara L Green, Hashan S M Jayarathne, Dulmalika N H Manchanayake, Sandra M Le, Penelope Lialios, Lucia E Breuer, Shoshana Yakar, Reji Babygirija, Michelle M Sonsalla, Isaac Grunow, Chung-Yang Yeh, Yang Liu, Bailey A Knopf, William A Ricke, Teresa T Liu, Mariana Sadagurski, Dudley W Lamming

    Our goal is to understand how nutrient-responsive signaling pathways can be harnessed to promote health and longevity. Rapamycin, an inhibitor of the protein kinase mTOR, can improve both health and longevity in model organisms including mammals. Understanding and manipulating the mTOR signaling pathway through dietary, pharmaceutical or genetic interventions may provide insight into the treatment of age-related diseases, including diabetes, Alzheimer’s disease, cancer, and Hutchinson-Gilford Progeria Syndrome.